The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 02, 2016

Filed:

Mar. 15, 2013
Applicant:

Universität Bern, Bern, CH;

Inventors:

Christian Leumann, Bern, CH;

Branislav Dugovic, Bern, CH;

Jory Liétard, Bern, CH;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); C07H 21/00 (2006.01); C07H 19/16 (2006.01); C07H 19/04 (2006.01); C07H 19/02 (2006.01); C07H 19/06 (2006.01);
U.S. Cl.
CPC ...
C07H 21/00 (2013.01); C07H 19/02 (2013.01); C07H 19/04 (2013.01); C07H 19/06 (2013.01); C07H 19/16 (2013.01);
Abstract

The present invention provides novel tricyclic nucleosides and oligomeric compounds prepared therefrom. Incorporation of one or more of the tricyclic nucleosides into an oligomeric compound is expected to enhance one or more properties of the oligomeric compound. Such oligomeric compounds can also be included in double stranded compositions. In certain embodiments, the oligomeric compounds provided herein are expected to hybridize to a portion of a target RNA resulting in loss of normal function of the target RNA.


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