The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2016
Filed:
Jun. 27, 2014
Applicant:
K.u. Leuven Research & Development, Leuven, BE;
Inventors:
Piet Herdewijn, Wezemaal, BE;
Christophe Pannecouque, Heverlee, BE;
Tongfei Wu, Leuven, BE;
Erik De Clercq, Bierbeek, BE;
Assignee:
K.U. Leuven Research & Development, Leuven, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/20 (2006.01); C07H 19/10 (2006.01); C07H 19/048 (2006.01); C07H 19/00 (2006.01); C07H 19/06 (2006.01); C07H 19/16 (2006.01); C07H 1/00 (2006.01);
U.S. Cl.
CPC ...
C07H 19/20 (2013.01); C07H 1/00 (2013.01); C07H 19/00 (2013.01); C07H 19/06 (2013.01); C07H 19/10 (2013.01); C07H 19/16 (2013.01);
Abstract
The invention is directed to processes of preparing phosphonate nucleosides comprising a phosphonalkoxy-substituted five-membered, saturated or unsaturated, oxygen-containing ring coupled to a heterocyclic nucleobase such as a pyrimidine or purine base. These compounds can be described by the general formula (XIX)