The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 02, 2016

Filed:

Mar. 04, 2011
Applicants:

Jessica Taylor, Dorking, GB;

Daniel Paul Hardy, Baldock, GB;

Rosemary Lynch, Cambridge, GB;

Helen Sarah Niblock, Kidlington, GB;

Andrew David Cansfield, Harston, GB;

Inventors:

Jessica Taylor, Dorking, GB;

Daniel Paul Hardy, Baldock, GB;

Rosemary Lynch, Cambridge, GB;

Helen Sarah Niblock, Kidlington, GB;

Andrew David Cansfield, Harston, GB;

Assignee:

CELLZOME LIMITED, Cambridge, GB;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); C07D 413/14 (2006.01); C07D 239/42 (2006.01); C07D 401/04 (2006.01); C07D 413/04 (2006.01); C07D 498/08 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); A61K 31/5377 (2013.01); C07D 239/42 (2013.01); C07D 401/04 (2013.01); C07D 413/04 (2013.01); C07D 498/08 (2013.01);
Abstract

The invention relates to compounds of formula (I) wherein X, X, Rto R, m, and n have the meaning as cited in the description and the claims. The compounds are useful as inhibitors of mTOR for the treatment or prophylaxis of mTOR related diseases and disorders. The invention also relates to pharmaceutical compositions including the compounds, the preparation of such compounds as well as the use as medicaments.


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