The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2016
Filed:
Jan. 31, 2012
Qiang Zhang, Shanghai, CN;
Rongxia Zhang, Shanghai, CN;
Guanghui Tian, Shanghai, CN;
Jianfeng LI, Shanghai, CN;
Fuqiang Zhu, Shanghai, CN;
Xiangrui Jiang, Shanghai, CN;
Jingshan Shen, Shanghai, CN;
Qiang Zhang, Shanghai, CN;
Rongxia Zhang, Shanghai, CN;
Guanghui Tian, Shanghai, CN;
Jianfeng Li, Shanghai, CN;
Fuqiang Zhu, Shanghai, CN;
Xiangrui Jiang, Shanghai, CN;
Jingshan Shen, Shanghai, CN;
Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, CN;
Topharman Shanghai Co., Ltd., Shanghai, CN;
Abstract
The present invention relates to a (2R,3R)-3-(3-substituted phenyl)-2-methyl n-pentanamide compounds as shown in the formula I and the preparation method thereof, wherein, the substituents are as defined in the specification, the present invention further relates to a use of the above compounds for the preparation of tapentadol II or its pharmaceutically acceptable salt, and the intermediates involved in the preparation process.