The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2016
Filed:
Oct. 29, 2012
Applicants:
Young Jun Kim, Yongin, KR;
Drew M. Pardoll, Brookeville, MD (US);
Charles George Drake, Baltimore, MD (US);
Meghan Davis, Baltimore, MD (US);
Juan Fu, Baltimore, MD (US);
Inventors:
Young Jun Kim, Yongin, KR;
Drew M. Pardoll, Brookeville, MD (US);
Charles George Drake, Baltimore, MD (US);
Meghan Davis, Baltimore, MD (US);
Juan Fu, Baltimore, MD (US);
Assignee:
The Johns Hopkins University, Baltimore, MD (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); C12N 15/27 (2006.01); A61K 35/12 (2015.01); A61K 39/00 (2006.01); A61K 45/06 (2006.01); A61K 38/19 (2006.01); A61K 31/7024 (2006.01); A61K 31/739 (2006.01); A61K 35/36 (2015.01); A61K 35/38 (2015.01); A61K 35/39 (2015.01); A61K 35/55 (2015.01); A61K 38/12 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0005 (2013.01); A61K 31/7024 (2013.01); A61K 31/739 (2013.01); A61K 35/12 (2013.01); A61K 35/36 (2013.01); A61K 35/38 (2013.01); A61K 35/39 (2013.01); A61K 35/55 (2013.01); A61K 38/193 (2013.01); A61K 39/0011 (2013.01); A61K 45/06 (2013.01); A61K 2039/5152 (2013.01); A61K 2039/5156 (2013.01); A61K 2039/55511 (2013.01); A61K 2039/55522 (2013.01); A61K 2039/55572 (2013.01);
Abstract
The invention provides provides immunogenic compositions comprising neoplastic cells expressing a cytokine (GM-CSF) formulated with at least one TLR agonist and methods of using the composition to induce or enhance an immune response.