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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9248164 B1

PDFFull Text
Date of Patent:
Feb. 02, 2016

Filed:

Mar. 26, 2012

Growth factor anchoring type bone graft material, method for producing growth factor anchoring type bone graft material, kit for producing growth factor anchoring type bone graft material, and method for forming bone

Applicants:

Kentaro Uchida, Sagamihara, JP;

Koji Naruse, Sagamihara, JP;

Masashi Takaso, Sagamihara, JP;

Takehiko Mima, Sagamihara, JP;

Osamu Matsushita, Sagamihara, JP;

Takashi Haraguchi, Sagamihara, JP;

Nozomu Nishi, Kagawa, JP;

Inventors:

Kentaro Uchida, Sagamihara, JP;

Koji Naruse, Sagamihara, JP;

Masashi Takaso, Sagamihara, JP;

Takehiko Mima, Sagamihara, JP;

Osamu Matsushita, Sagamihara, JP;

Takashi Haraguchi, Sagamihara, JP;

Nozomu Nishi, Kagawa, JP;

Assignees:

SCHOOL JURIDICAL PERSON KITASATO INSTITUTE, Tokyo, JP;

NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY, Takamatsu-Shi, Kagawa, JP;

Attorney:

Birch, Stewart, Kolasch & Birch, LLP

Primary Examiner:

Elizabeth C Kemmerer

Int. Cl.
CPC ...
A61K 38/18 (2006.01); A61K 9/70 (2006.01); A61K 47/42 (2006.01); A61L 27/54 (2006.01); A61K 38/48 (2006.01); A61L 27/36 (2006.01); C07K 14/33 (2006.01); C07K 14/485 (2006.01); C12N 9/52 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1825 (2013.01); A61K 38/1808 (2013.01); A61K 38/4886 (2013.01); A61L 27/3608 (2013.01); A61L 27/54 (2013.01); C07K 14/33 (2013.01); C07K 14/485 (2013.01); C12N 9/52 (2013.01); A61L 2300/252 (2013.01); A61L 2300/414 (2013.01); A61L 2430/02 (2013.01); C07K 2319/00 (2013.01); C07K 2319/003 (2013.01); C07K 2319/70 (2013.01);
Abstract

Provided is a growth factor anchoring type bone graft material, wherein a bone graft substrate exposing at least a collagen fiber is bound to a collagen-binding-site-containing growth factor which contains a growth factor receptor agonist peptide and a collagen-binding peptide. The same can be produced by mixing a bone graft substrate and a collagen-binding-site-containing growth factor which contains a growth factor receptor agonist peptide and a collagen-binding peptide, and is also superior in osteogenic ability.

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