The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 02, 2016

Filed:

Jan. 11, 2013
Applicants:

California Institute of Technology, Pasadena, CA (US);

University of Southern California, Los Angeles, CA (US);

Inventors:

Yu-Chong Tai, Pasadena, CA (US);

Bo Lu, Pasadena, CA (US);

Mark Humayun, Glendale, CA (US);

Assignees:

California Institute of Technology, Pasadena, CA (US);

University of Southern California, Los Angeles, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61F 2/04 (2013.01); C12N 5/00 (2006.01); A61L 27/18 (2006.01); A61L 27/38 (2006.01);
U.S. Cl.
CPC ...
A61F 2/04 (2013.01); A61L 27/18 (2013.01); A61L 27/3804 (2013.01); C12N 5/0068 (2013.01); A61L 2430/16 (2013.01); C12N 2533/30 (2013.01);
Abstract

Thin parylene C membranes having smooth front sides and ultrathin regions (e.g., 0.01 μm to 5 μm thick) interspersed with thicker regions are disclosed. The back sides of the membranes can be rough compared with the smooth front sides. The membranes can be used in vitro to grow monolayers of cells in a laboratory or in vivo as surgically implantable growth layers, such as to replace the Bruch's membrane in the eye. The application further provides an implantable cage-like apparatus for culturing cells comprising the parylene membrane.


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