The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 26, 2016
Filed:
Sep. 30, 2014
Applicant:
Rifaat Safadi, Nazareth Elit, IL;
Inventor:
Rifaat Safadi, Nazareth Elit, IL;
Assignee:
Hadasit Medical Research Services and Development Ltd., Jerusalem, IL;
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12Q 1/68 (2006.01); A61K 31/7088 (2006.01); A61K 45/06 (2006.01); C12N 15/113 (2010.01); A61K 31/713 (2006.01); A61K 31/7105 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); A61K 45/06 (2013.01); C12N 15/1138 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); C12Q 2600/158 (2013.01);
Abstract
The present invention provides a method of treating, attenuating or preventing a liver disorder by inhibiting NLGn4 expression and thereby modulating the activity of NK cells. The present invention further relates to diagnosing a liver disorder by evaluating NLGn4 expression in NK cells.