The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 26, 2016
Filed:
Jul. 22, 2013
Applicant:
Intrexon Corporation, Blacksburg, VA (US);
Inventors:
Robert E. Hormann, Melrose Park, PA (US);
Silvia Lapenna, Leghorn, IT;
Laurence Neil Dinan, Dorset, GB;
Assignee:
Intrexon Corporation, Blacksburg, VA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/575 (2006.01); C07C 13/66 (2006.01); C07C 49/753 (2006.01); C07C 49/727 (2006.01); C12N 15/85 (2006.01); C07J 9/00 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01); A61K 31/575 (2013.01); C07C 49/727 (2013.01); C07C 49/753 (2013.01); C07J 9/00 (2013.01); C07K 14/70567 (2013.01); C07K 2319/715 (2013.01); C12N 2830/002 (2013.01);
Abstract
The present invention relates to steroidal ligands for use in nuclear receptor-based inducible gene expression systems. The invention further relates to methods of modulating the expression of genes of interest with a system containing one or more nuclear receptor complexes and one or more steroidal ligands. Further aspects include ligand compositions including therapeutic compositions.