The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 26, 2016

Filed:

Jul. 01, 2014
Applicant:

Polyplus-transfection SA, Illkirch, FR;

Inventors:

Jean-Paul Behr, Strasbourg, FR;

Anne-Laure Bolcato Bellemin, Strasbourg, FR;

Patrick Erbacher, Benfeld, FR;

Assignee:

POLYPLUS-TRANSFECTION SA, Illkirch, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 15/11 (2006.01); A61K 31/713 (2006.01); A61K 47/34 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 31/713 (2013.01); A61K 47/34 (2013.01); C12N 15/111 (2013.01); C12N 2310/14 (2013.01); C12N 2310/51 (2013.01); C12N 2320/30 (2013.01); C12N 2320/51 (2013.01); C12N 2320/52 (2013.01);
Abstract

The invention relates to compositions comprising double-stranded oligonucleotides of identical or different sequences and/or length, said oligonucleotides having sequencesNN. . . NN. . . Nwherein—N. . . Nis half of a double-stranded 19-28 mer oligonucleotide of sequence complementary to a target nucleic acid sequence present in a living cell, and—N. . . Nis a 3-50 mer overhang of sequence allowing oligomerization of said double-stranded oligonucleotide. Compositions of transfection comprising said oligonucleotide compositions and there used for therapeutical application.


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