The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 26, 2016
Filed:
Aug. 19, 2011
Lee Lim, San Francisco, CA (US);
Guillaume Chorn, Hong Kong, CN;
Aarron Willingham, Mountain View, CA (US);
Lihong Zhao, Walnut Creek, CA (US);
Lee Lim, San Francisco, CA (US);
Guillaume Chorn, Hong Kong, CN;
Aarron Willingham, Mountain View, CA (US);
Lihong Zhao, Walnut Creek, CA (US);
Sirna Therapeutics, Inc., Cambridge, MA (US);
Abstract
Single-stranded RNA molecules comprise one or more internal, non-nucleotide spacers, covalently linked with nucleotide portions of the molecule are provided. The single-stranded RNA molecules function as guide or antisense strands that are capable of inhibiting gene expression via an RNA interference mechanism, and thus represent single-stranded RNAi agents. The single-stranded RNAi molecules can be used in methods for a variety of therapeutic, diagnostic, target validation, genomic discovery, genetic engineering, and pharmacogenomic applications.