The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 26, 2016
Filed:
May. 04, 2012
Isabelle DE Waziers, Paris, FR;
Walid Touati, Paris, FR;
Monique Diry, Paris, FR;
Jean-pierre Flinois, Paris, FR;
Patrick Dansette, Paris, FR;
Philippe Beaune, Paris, FR;
Isabelle De Waziers, Paris, FR;
Walid Touati, Paris, FR;
Monique Diry, Paris, FR;
Jean-Pierre Flinois, Paris, FR;
Patrick Dansette, Paris, FR;
Philippe Beaune, Paris, FR;
Abstract
The present invention to relates mutant human cytochrome P450 2B6 (CYP2B6) proteins, and fusion proteins comprising said mutant CYP2B6 proteins. In particular, fusion proteins comprising mutant CYP2B6 and NAPDH-cytochrome P450 reductase are provided. The invention also relates to methods of treatment of cancer and the use of said proteins and fusion proteins in the treatment of cancer, in particular via virus-directed enzyme prodrug therapy.