The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 26, 2016
Filed:
Nov. 09, 2012
Applicant:
Trustees of Boston College, Chestnut Hill, MA (US);
Inventors:
Jianmin Gao, Newton, MA (US);
Fang Wang, Brighton, MA (US);
Assignee:
Trustees of Boston College, Chestnut Hill, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A01N 37/18 (2006.01); A61K 38/00 (2006.01); A61P 31/04 (2006.01); C07K 7/28 (2006.01); A61K 38/10 (2006.01); A01N 43/38 (2006.01);
U.S. Cl.
CPC ...
C07K 7/28 (2013.01); A01N 43/38 (2013.01); A61K 38/10 (2013.01); A61K 38/00 (2013.01);
Abstract
Described herein are antimicrobial peptides for use in pharmaceutical antibiotic compositions and methods of use thereof. These antimicrobial peptides are Gramicidin A (gA) peptide analogs that, in addition to having potent anti-microbial activity, have greatly increased solubility and significantly reduced toxicity in comparison to the wild-type Gramicidin A peptide.