The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 26, 2016
Filed:
Jan. 26, 2012
Hagit Eldar-finkelman, Shoham, IL;
Avital Licht-murava, Tel-Aviv, IL;
Batya Plotkin, Rishon-LeZion, IL;
Hagit Eldar-Finkelman, Shoham, IL;
Avital Licht-Murava, Tel-Aviv, IL;
Batya Plotkin, Rishon-LeZion, IL;
Ramot at Tel-Aviv University Ltd., Tel-Aviv, IL;
Abstract
Novel peptide inhibitors of GSK-3, compositions containing same and uses thereof are disclosed. The novel peptide inhibitors are substrate-competitive inhibitors and have an amino acid sequence designed so as to bind to a defined binding site subunit in GSK-3. Also disclosed are GSK-3 substrate competitive inhibitors which bind to the defined binding site subunit in the enzyme. Also disclosed are mutants of GSK-3 and uses thereof for identifying a putative GSK-3 substrate competitive inhibitor.