The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 26, 2016

Filed:

Oct. 11, 2012
Applicant:

Morgan State University, Baltimore, MD (US);

Inventor:

Kadir Aslan, Baltimore, MD (US);

Assignee:

Morgan State University, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C30B 29/56 (2006.01); C07H 1/06 (2006.01); C07C 227/42 (2006.01); C30B 7/00 (2006.01); C30B 28/06 (2006.01); C30B 29/58 (2006.01);
U.S. Cl.
CPC ...
C07H 1/06 (2013.01); C07C 227/42 (2013.01); C30B 7/005 (2013.01); C30B 28/06 (2013.01); C30B 29/58 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention relates to methods for rapid crystallization of amino acids, drug molecules, proteins and DNA/peptides. One method for rapid crystallization of functional group-containing molecules selected from the group consisting of amino acids, drug molecules, proteins and DNA/peptides includes (A) providing at least one metal or metal oxide in particulate or thin film form to provide (a) selective nucleation sites for crystallization of the functional group-containing molecules due to interactions of their functional groups and metal surfaces or engineered metal surfaces and (b) a microwave-transparent medium to create a thermal gradient between the metal surfaces or engineered metal surfaces and a warmer solution containing functional group-containing molecules to be crystallized, and (B) conducting microwave heating to cause the functional group-containing molecules to be crystallized.


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