The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 26, 2016
Filed:
Oct. 05, 2012
Applicant:
Cellzome Limited, Middlesex, GB;
Inventors:
Rosemary Lynch, Cambridge, GB;
Andrew David Cansfield, Cambridge, GB;
Daniel Paul Hardy, Baldock, GB;
John Thomas Feutrill, Rosanna, AU;
Rita Adrego, Brandon, GB;
Katie Ellard, Herts, GB;
Tammy Ladduwahetty, Longon, GB;
Assignee:
CELLZOME LIMITED, Brentford, Middlesex, GB;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/5386 (2006.01); A61K 31/519 (2006.01); C07D 417/02 (2006.01); C07D 495/04 (2006.01); C07D 498/08 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); A61K 31/519 (2013.01); A61K 31/5377 (2013.01); A61K 31/5386 (2013.01); C07D 417/02 (2013.01); C07D 498/08 (2013.01);
Abstract
The invention relates to compounds of formula (I) wherein m, o, R, R, Rand Thave the meaning as cited in the description and the claims. The compounds are useful as inhibitors of mTOR for the treatment or prophylaxis of mTOR related diseases and disorders. The invention also relates to pharmaceutical compositions including the compounds, the preparation of the compounds as well as their use as medicaments.