The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 26, 2016
Filed:
May. 08, 2014
Applicants:
Shionogi & Co., Ltd., Osaka, JP;
Viiv Healthcare Company, Research Triangle Park, NC (US);
Inventors:
Takashi Kawasuji, Osaka, JP;
Daiki Nagamatsu, Osaka, JP;
Assignees:
SHIONOGI & CO., LTD., Osaka, JP;
ViiV Healthcare Company, Research Triangle Park, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/22 (2006.01); A61K 31/351 (2006.01); A61K 31/4412 (2006.01); C07D 487/22 (2006.01); C07D 498/14 (2006.01);
U.S. Cl.
CPC ...
C07D 471/22 (2013.01); A61K 31/351 (2013.01); A61K 31/4412 (2013.01); C07D 487/22 (2013.01); C07D 498/14 (2013.01);
Abstract
A synthesis approach providing an early ring attachment via a bromination to compound 1-1 yielding compound II-II, whereby a final product such as AA can be synthesized. In particular, the 2,4-difluorophenyl-containing sidechain is attached before creation of the additional ring Q.
Kawasuji, Takashi. (2016). Synthesis of carbamoylpyridone hiv integrase inhibitors and intermediates (U.S. Patent No. 9242986). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9242986
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