The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 26, 2016

Filed:

Aug. 24, 2012
Applicants:

Ronald Kühne, Berlin, DE;

Hartmut Oschkinat, Berlin, DE;

Robert Opitz, Berlin, DE;

Matthias Müller, Berlin, DE;

Hans-günther Schmalz, Brühl, DE;

Cedric Reuter, Köln, DE;

Peter Huy, Korschenbroich, DE;

Inventors:

Ronald Kühne, Berlin, DE;

Hartmut Oschkinat, Berlin, DE;

Robert Opitz, Berlin, DE;

Matthias Müller, Berlin, DE;

Hans-Günther Schmalz, Brühl, DE;

Cedric Reuter, Köln, DE;

Peter Huy, Korschenbroich, DE;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 37/18 (2006.01); A61K 38/04 (2006.01); C07D 471/20 (2006.01); A61K 31/437 (2006.01); C07K 5/078 (2006.01); C07K 7/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/20 (2013.01); A61K 31/437 (2013.01); C07K 5/06139 (2013.01); C07K 7/06 (2013.01); A61K 38/00 (2013.01);
Abstract

The invention relates to compounds that can be used, in particular, as structural mimetics of proline-rich peptides and are correspondingly able to bond with proline-rich-motif binding domains (PRM domains) of proteins. The invention further relates to the use of these compounds as pharmaceutically active agents, as well as the use of the pharmaceutically active agents for the treatment of bacterial, neurodegenerative and tumor diseases.


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