The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 26, 2016
Filed:
Sep. 25, 2013
Kowa Company, Ltd., Aichi, JP;
Takahisa Ogamino, Tokyo, JP;
Shin Tanikawa, Tokyo, JP;
Yoshiharu Miyake, Tokyo, JP;
Shinsuke Itoh, Tokyo, JP;
Yoshikazu Sawada, Tokyo, JP;
Kowa Company, Ltd., Aichi, JP;
Abstract
The present invention is to create a compound that selectively activates glucokinase in the liver, and in particular, to provide an agent for treating and preventing diabetes and impaired glucose tolerance, wherein the agent has a low hypoglycemia risk. A compound represented by the formula (1) as shown below, or a salt thereof, or a solvate of the compound or the salt: wherein, in the following formula (1), ring A represents a thiazolyl group, a pyridyl group, a pyrazyl group, or a pyrazolyl group; L represents —(CO)—, —(CS)—, or —SO—; and Rrepresents a Calkyl group, a hydroxy Calkyl group, a Calkoxy group, an amino group, a Calkylamino group, a hydroxyamino group, an N—Calkylcarbamoyl group, or a group represented by the formula (2) as shown below, wherein Rrepresents a Calkyl group; and Rrepresents a hydrogen atom, a halogen atom, a Calkyl group, a Calkoxy group, or a carboxyl group. The formulas are shown below: