The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 26, 2016
Filed:
Jan. 12, 2012
Matteo Andreini, Siena, IT;
Emanuele Gabellieri, Siena, IT;
Wolfgang Guba, Muellheim, DE;
Hans Hilpert, Muenchenstein, CH;
Alexander V. Mayweg, Shanghai, CN;
Robert Narquizian, Zaessingue, FR;
Eoin Power, Blackrock, IE;
Massimiliano Travagli, Siena, IT;
Thomas Woltering, Freiburg, DE;
Wolfgang Wostl, Grenzach-Wyhlen, DE;
Harald Mauser, Riehen, CH;
Matteo Andreini, Siena, IT;
Emanuele Gabellieri, Siena, IT;
Wolfgang Guba, Muellheim, DE;
Hans Hilpert, Muenchenstein, CH;
Alexander V. Mayweg, Shanghai, CN;
Robert Narquizian, Zaessingue, FR;
Eoin Power, Blackrock, IE;
Massimiliano Travagli, Siena, IT;
Thomas Woltering, Freiburg, DE;
Wolfgang Wostl, Grenzach-Wyhlen, DE;
Harald Mauser, Riehen, CH;
SIENA BIOTECH S.P.A., Siena, IT;
HOFFMANN-LA ROCHE INC., Nutley, NJ (US);
Abstract
The present invention relates to 1,4 Oxazines of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes.