The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 26, 2016

Filed:

Jun. 26, 2009
Applicants:

Anders Høgset, Oslo, NO;

Anette Weyergang, Oslo, NO;

P{dot Over (A)}l Kristian Selbo, Oslo, NO;

Kristian Berg, Heggedal, NO;

Inventors:

Anders Høgset, Oslo, NO;

Anette Weyergang, Oslo, NO;

P{dot over (a)}l Kristian Selbo, Oslo, NO;

Kristian Berg, Heggedal, NO;

Assignee:

PCI BIOTECH AS, Oslo, NO;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 63/02 (2006.01); A01N 63/00 (2006.01); C12N 5/071 (2010.01); C12N 5/02 (2006.01); A61K 31/50 (2006.01); A61K 31/4965 (2006.01); A61K 31/517 (2006.01); A01N 43/38 (2006.01); A61K 31/40 (2006.01); A61K 41/00 (2006.01); A61K 31/00 (2006.01); A61K 31/501 (2006.01); A01N 43/90 (2006.01); A01N 43/54 (2006.01); A61K 31/505 (2006.01); A01N 43/42 (2006.01); A61K 31/445 (2006.01); A01N 43/40 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0071 (2013.01); A61K 31/00 (2013.01);
Abstract

The present invention relates to a method for enhancing the activity of kinase inhibitors in target cells, and more specifically for enhancing the activity of tyrosine kinase inhibitors (TKIs), said method comprising contacting a cell with a kinase inhibitor and a photosensitizing agent and irradiating said cell with light of a wavelength effective to activate the photosensitizing agent, and to the use of this method for enhancing the effects of kinase inhibitors or kinase inhibitor-based drugs in particular to achieve cell death, for example, in cancer treatment and other diseases or conditions in which kinase inhibitors, such as TKIs, have a beneficial effect.


Find Patent Forward Citations

Loading…