The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 26, 2016

Filed:

Dec. 19, 2014
Applicants:

Carlos Garcia-echeverria, Saint-Cloud, FR;

Sauveur-michel Maira, Habsheim, FR;

Darrin Stuart, Pleasant Hill, CA (US);

Susan Wee, Skillman, NJ (US);

Christine Fritsch, Steinbach, FR;

Tobi Nagel, Oakland, CA (US);

Inventors:

Carlos Garcia-Echeverria, Saint-Cloud, FR;

Sauveur-Michel Maira, Habsheim, FR;

Darrin Stuart, Pleasant Hill, CA (US);

Susan Wee, Skillman, NJ (US);

Christine Fritsch, Steinbach, FR;

Tobi Nagel, Oakland, CA (US);

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); A61K 31/4745 (2006.01); A61K 31/4188 (2006.01); A61K 45/06 (2006.01); A61K 31/166 (2006.01); A61K 31/437 (2006.01); A61K 31/4439 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4745 (2013.01); A61K 31/166 (2013.01); A61K 31/4188 (2013.01); A61K 31/437 (2013.01); A61K 31/4439 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01);
Abstract

The invention relates to a pharmaceutical combination which comprises (a) a phosphoinositide 3-kinase inhibitor compound and (b) a compound which modulates the Ras/Raf/Mek pathway for the treatment of a proliferative disease, especially a solid tumor disease; a pharmaceutical composition comprising such a combination; the use of such a combination for the preparation of a medicament for the treatment of a proliferative disease; a commercial package or product comprising such a combination as a combined preparation for simultaneous, separate or sequential use; and to a method of treatment of a warm-blooded animal, especially a human.


Find Patent Forward Citations

Loading…