The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 26, 2016

Filed:

Oct. 29, 2012
Applicants:

Iannis Aifantis, Brooklyn, NY (US);

Linsey Reavie, Binningen, CH;

Shannon Buckley, New York, NY (US);

Inventors:

Iannis Aifantis, Brooklyn, NY (US);

Linsey Reavie, Binningen, CH;

Shannon Buckley, New York, NY (US);

Assignee:

NEW YORK UNIVERSITY, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61K 31/196 (2006.01); A61K 45/06 (2006.01); A61K 38/17 (2006.01); A61N 5/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/196 (2013.01); A61K 31/506 (2013.01); A61K 38/1709 (2013.01); A61K 45/06 (2013.01); A61N 5/10 (2013.01);
Abstract

The present invention is directed to methods of inhibiting cancer cell proliferation, differentiation and/or survival. These methods involve the administration of Fbw7 E3 ligase inhibitors to inhibit c-Myc ubiquitination in cancerous cell populations, such as leukemic initiating cell populations, that are responsible for disease initiation and progression.


Find Patent Forward Citations

Aifantis, Iannis. (2016). Inhibition of c-myc ubiquitination to prevent cancer initiation and progression (U.S. Patent No. 9241920). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9241920

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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