The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 19, 2016
Filed:
Sep. 08, 2009
Applicants:
Haiming Cao, Bethesda, MD (US);
Gokhan S. Hotamisligil, Wellesley, MA (US);
Inventors:
Haiming Cao, Bethesda, MD (US);
Gokhan S. Hotamisligil, Wellesley, MA (US);
Assignee:
PRESIDENT AND FELLOWS OF HARVARD COLLEGE, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 37/00 (2006.01); A61K 31/20 (2006.01); G01N 33/92 (2006.01); A23L 1/30 (2006.01);
U.S. Cl.
CPC ...
G01N 33/92 (2013.01); A23L 1/3008 (2013.01); A61K 31/20 (2013.01); G01N 2800/04 (2013.01);
Abstract
The present invention provides for a novel lipokine, C16:1n7-palmitoleate, which also serves as a biomarker for metabolic status. More specifically, a low concentration of C16:1n7-palmitoleate in the free fatty acid component of the serum indicates a risk of metabolic disease, and that de novo lipogenesis should be stimulated. Additionally, administering C16:1n7-palmitoleate to a subject (via nutraceutical or other means), positively impacts lipid metabolism.