The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 19, 2016
Filed:
Dec. 10, 2010
Megan Shaw, New York, NY (US);
Peter Palese, Leonia, NJ (US);
Adolfo Garcia-sastre, New York, NY (US);
Silke Stertz, Zurich, CH;
John Young, San Diego, CA (US);
Renate König, San Diego, CA (US);
Sumit Chanda, La Jolla, CA (US);
Megan Shaw, New York, NY (US);
Peter Palese, Leonia, NJ (US);
Adolfo Garcia-Sastre, New York, NY (US);
Silke Stertz, Zurich, CH;
John Young, San Diego, CA (US);
Renate König, San Diego, CA (US);
Sumit Chanda, La Jolla, CA (US);
Icahn School of Medicine at Mounta Sinai, New York, NY (US);
Salk Institute for Biological Studies, La Jolla, CA (US);
Sanford-Burnham Medical Research Institute, La Jolla, CA (US);
Abstract
This application relates to the modulation of host cell factors required for influenza virus replication. The application relates to compounds, including nucleic acid compounds (such as, e.g., small interfering RNAs (siRNAs)) and small molecules, that target human host cell factors involved in influenza virus replication, and the use of such compounds for modulating influenza virus replication and as antiviral agents. The application also relates to methods of treating an influenza virus infection and methods of treating or preventing a symptom or disease associated with influenza virus infection, comprising administering to a subject a composition comprising a compound, such as a nucleic acid compound (e.g., an siRNA) or small molecule, that targets a human host cell factor involved in influenza virus replication.