The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 19, 2016
Filed:
Oct. 29, 2009
Ewa Zuziak, Wroclaw, PL;
Andrzej Gamian, Wroclaw, PL;
Andrzej Górski, Wroclaw, PL;
Tomasz Lipiński, Wroclaw, PL;
Ewa Zuziak, Wroclaw, PL;
Andrzej Gamian, Wroclaw, PL;
Andrzej Górski, Wroclaw, PL;
Tomasz Lipiński, Wroclaw, PL;
Instytut Immunologii I Terapii Doswiadczalnej Pan, Wroclaw, PL;
Abstract
The subject the present invention is a method of producing a pharmacologically stable form of purified and lyophilised bacteriophage preparations of increased stability and antibacterial activity, characterized in that phages produced from a bacterial lysate, for example by ultrafiltration on ultrafiltration membranes, containing a high molecular weight preparation of purified phages is stabilised most preferably with a probiotic extract in the presence or absence of neutral salts and/or organic solvents, lyophilised, characterised via HPLC chromatography, by SDS-PAGE, and bacterial lysis biological assays, and then stored under a vacuum, where the active lyophilisate is destined for phage therapy of infections and tumors.