The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 19, 2016
Filed:
Jul. 07, 2009
Tatsuji Enoki, Otsu, JP;
Fumiko Iwamoto, Otsu, JP;
Toshikazu Nishie, Otsu, JP;
Takahiro Marui, Otsu, JP;
Fuyuko Takashima, Otsu, JP;
Ikunoshin Kato, Otsu, JP;
Tatsuji Enoki, Otsu, JP;
Fumiko Iwamoto, Otsu, JP;
Toshikazu Nishie, Otsu, JP;
Takahiro Marui, Otsu, JP;
Fuyuko Takashima, Otsu, JP;
Ikunoshin Kato, Otsu, JP;
TAKARA BIO INC., Shiga, JP;
Abstract
The present invention relates to a method for production of a cell population containing a pluripotent stem cell, said method comprising a step of treating a somatic cell which has been contacted with nuclear reprogramming factors under nutrient-starved condition, and/or a step of treating the somatic cell with an agent capable of arresting cell cycle. The present invention allows induction and growth of pluripotent stem cells at high frequency, and it also allows production of pluripotent stem cells with high efficiency. The nuclear reprogramming factors to be used may be any selected from the group consisting of OCT4, SOX2, c-MYC, KLF4, NANOG and LIN28.