The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 19, 2016

Filed:

Jun. 13, 2012
Applicants:

Sanjay Sinha, Cambridge, GB;

Roger Pedersen, Cambridge, GB;

Andreia Bernardo, Cambridge, GB;

Christine Cheung, Cambridge, GB;

Inventors:

Sanjay Sinha, Cambridge, GB;

Roger Pedersen, Cambridge, GB;

Andreia Bernardo, Cambridge, GB;

Christine Cheung, Cambridge, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/077 (2010.01); C12N 5/071 (2010.01); C12N 5/073 (2010.01); C12N 5/0775 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0661 (2013.01); C12N 5/0662 (2013.01); C12N 5/0691 (2013.01); C12N 2501/115 (2013.01); C12N 2501/155 (2013.01); C12N 2506/03 (2013.01);
Abstract

This invention relates to the production of populations of Smooth Muscle Cells (SMCs) of specific embryonic lineages, such as neuroectodermal and mesodermal SMCs. Pluripotent stem cells are cultured in one or more lineage induction media to produce progenitor cells of a defined embryonic lineage, which are then cultured in an SMC induction medium to produce a population of SMCs of the embryonic lineage. Populations of SMCs of defined lineages may be useful, for example, in accurately modelling vascular disease.


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