The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 19, 2016

Filed:

Jun. 15, 2011
Applicants:

Masao Tanihara, Ikoma, JP;

Kana Takaichi, Takatsuki, JP;

Mariko Maeda, Takatsuki, JP;

Tsukasa Mitsui, Takatsuki, JP;

Kazushi Yamamoto, Takatsuki, JP;

Akiko Hirano, Takatsuki, JP;

Inventors:

Masao Tanihara, Ikoma, JP;

Kana Takaichi, Takatsuki, JP;

Mariko Maeda, Takatsuki, JP;

Tsukasa Mitsui, Takatsuki, JP;

Kazushi Yamamoto, Takatsuki, JP;

Akiko Hirano, Takatsuki, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/78 (2006.01); A61Q 19/08 (2006.01); A61Q 19/00 (2006.01); C07K 1/107 (2006.01); A61K 8/67 (2006.01); A61K 31/07 (2006.01); A61K 38/39 (2006.01); A61Q 1/00 (2006.01); A61Q 1/02 (2006.01); A61Q 1/12 (2006.01); A61Q 5/02 (2006.01); A61Q 5/12 (2006.01); A61Q 19/10 (2006.01);
U.S. Cl.
CPC ...
C07K 14/78 (2013.01); A61K 8/671 (2013.01); A61K 31/07 (2013.01); A61K 38/39 (2013.01); A61Q 19/00 (2013.01); A61Q 19/08 (2013.01); C07K 1/1077 (2013.01); A61Q 1/00 (2013.01); A61Q 1/02 (2013.01); A61Q 1/12 (2013.01); A61Q 5/02 (2013.01); A61Q 5/12 (2013.01); A61Q 19/10 (2013.01);
Abstract

Disclosed is a compound which exhibits a higher effect of preventing wrinkle formation, a higher effect of improving wrinkles, a higher effect of making the skin beautiful, and a higher effect of improving skin quality than conventional retinol and retinol derivatives in a sustained manner. Further disclosed are a method for producing the same, and an external composition for the skin and a sheet-shaped cosmetic each containing the same as an active ingredient. More specifically disclosed are retinol-modified collagen in which a dicarboxylic acid is attached to at least one hydroxyl group of collagen and retinol is attached to a carboxyl group of at least one attached dicarboxylic acid, a method for producing the same, and an external composition for the skin and a sheet-shaped cosmetic each containing the same as an active ingredient.


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