The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 19, 2016

Filed:

Jul. 30, 2012
Applicants:

Peter H. Seeberger, Kleinmachnow, DE;

Christopher E. Martin, Berlin, DE;

Felix Broecker, Berlin, DE;

Chakkumkal Anish, Berlin, DE;

Inventors:

Peter H. Seeberger, Kleinmachnow, DE;

Christopher E. Martin, Berlin, DE;

Felix Broecker, Berlin, DE;

Chakkumkal Anish, Berlin, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 15/04 (2006.01); C07H 3/06 (2006.01); C07H 5/04 (2006.01); C07H 3/08 (2006.01); C07H 13/08 (2006.01); C07H 15/20 (2006.01); C07K 16/12 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
C07H 3/06 (2013.01); C07H 3/08 (2013.01); C07H 5/04 (2013.01); C07H 13/08 (2013.01); C07H 15/04 (2013.01); C07H 15/20 (2013.01); C07K 16/1282 (2013.01); G01N 33/56911 (2013.01);
Abstract

The invention relates to a synthetic oligosaccharide representing part of the repeating unit of theglycopolymer PS-I and having the sequence of the pentasaccharide a-L-Rhap-(1→3)-β-D-Glcp-(1→4)-[a-L-Rhap-(1→3]-a-D-Glcp-(1→2)-a-D-Glcp or a synthetic fragment or derivative thereof. Preferably, the claimed synthetic oligosaccharide bears at least one linker L for conjugation to a carrier protein or for immobilization on a surface. Further aspects of the invention relate to advantageous methods for synthesizing said synthetic oligosaccharide and oligosaccharide-protein conjugate as well as to uses thereof, in particular as vaccines and diagnostic tools.


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