The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 19, 2016

Filed:

Sep. 28, 2010
Applicants:

Pradipsinh K. Rathod, Seattle, WA (US);

David Floyd, Pennington, NJ (US);

Jeremy Burrows, Geneva, CH;

Alka Marwaha, Seattle, WA (US);

Ramesh Gujjar, Seattle, WA (US);

Jose Coteron-lopez, Madrid, ES;

Margaret Phillips, Dallas, TX (US);

Susan A. Charman, Victoria, AU;

David Matthews, Encinitas, CA;

Inventors:

Pradipsinh K. Rathod, Seattle, WA (US);

David Floyd, Pennington, NJ (US);

Jeremy Burrows, Geneva, CH;

Alka Marwaha, Seattle, WA (US);

Ramesh Gujjar, Seattle, WA (US);

Jose Coteron-Lopez, Madrid, ES;

Margaret Phillips, Dallas, TX (US);

Susan A. Charman, Victoria, AU;

David Matthews, Encinitas, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61P 33/06 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01);
Abstract

Inhibitors of parasitic dihydroorotate dehydrogenase enzyme (DHOD) are candidate therapeutics for treating malaria. Illustrative of such therapeutic agents include the compound: and a triazolopyrimidine class of compounds that conform to Formula IX: and their solvates, stereoisomers, tautomers and pharmaceutically acceptable salts.


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