The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9238634 B1

PDF
Full Text
Expired
Date of Patent:
Jan. 19, 2016

Filed:

Aug. 04, 2011
Applicants:

Makoto Arita, Tokyo, JP;

Hiroyuki Arai, Tokyo, JP;

Yosuke Isobe, Tokyo, JP;

Tadafumi Kubota, Tokyo, JP;

Inventors:

Makoto Arita, Tokyo, JP;

Hiroyuki Arai, Tokyo, JP;

Yosuke Isobe, Tokyo, JP;

Tadafumi Kubota, Tokyo, JP;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/20 (2006.01); A01N 43/24 (2006.01); A61K 31/335 (2006.01); C07D 303/14 (2006.01); C07D 303/38 (2006.01); C12P 7/64 (2006.01); C12P 17/02 (2006.01); G01N 30/34 (2006.01); G01N 30/72 (2006.01); G01N 30/88 (2006.01);
U.S. Cl.
CPC ...
C07D 303/14 (2013.01); C07D 303/38 (2013.01); C12P 7/6427 (2013.01); C12P 17/02 (2013.01); C12Y 113/11 (2013.01); G01N 30/34 (2013.01); G01N 30/7233 (2013.01); G01N 2030/884 (2013.01);
Abstract

The purpose is to provide a compound which can overcomes the disadvantages of conventional steroid drugs and NSAID. It is found that specific epoxy monohydroxy forms of eicosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid which are independently represented by formulae [chemical formula 1], [chemical formula 5] and the like have an inhibitory activity on neutrophils. This compound can inhibit the invasion of neutrophils into tissues and the activation of neutrophils which are observed in acute inflammations.


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