The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 19, 2016

Filed:

May. 25, 2012
Applicants:

Gábor Havasi, Budapest, HU;

Tibor Kiss, Budapest, HU;

Irén Hortobágyi, Budapest, HU;

Zsuzsanna Kardos, Budapest, HU;

István Lászlófi, Budapest, HU;

Zoltán Bischof, Budapest, HU;

Ádám Bódis, Budapest, HU;

Inventors:

Gábor Havasi, Budapest, HU;

Tibor Kiss, Budapest, HU;

Irén Hortobágyi, Budapest, HU;

Zsuzsanna Kardos, Budapest, HU;

István Lászlófi, Budapest, HU;

Zoltán Bischof, Budapest, HU;

Ádám Bódis, Budapest, HU;

Assignee:

CHINOIN ZRT, Budapest, HU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 69/74 (2006.01); C07C 231/00 (2006.01); C07D 209/48 (2006.01); C07C 405/00 (2006.01); C07D 207/46 (2006.01); C07D 233/60 (2006.01); C07D 307/935 (2006.01); C07D 209/50 (2006.01);
U.S. Cl.
CPC ...
C07C 405/0041 (2013.01); C07C 405/00 (2013.01); C07D 207/46 (2013.01); C07D 209/48 (2013.01); C07D 209/50 (2013.01); C07D 233/60 (2013.01); C07D 307/935 (2013.01); C07B 2200/13 (2013.01); C07C 2101/08 (2013.01);
Abstract

The subject of the invention is process for the preparation of the prostaglandin amides of the general formula I, —where in the formula the bonds marked with dotted lines may be single or double bonds, in the case of double bounds at positions 5,6 and 13,14 they may be in cis or in trans orientation, Q stands for a hydroxyl-group and Z stands for a hydroxyl- or oxo-group, Rand Rindependently represent hydrogen atom or a straight or branched Calkyl- or aralkyl-group, optionally substituted with —ONOgroup, or an aralkyl- or aryl-group, which contains heteroatom, Rrepresents a straight or branched, saturated or unsaturated Chydrocarbon group, or a Calkylcycloalkyl- or cycloalkyl-group, or an optionally with alkyl group or halogen atom substituted phenyl-, Calkylaryl- or hetaryl-group, Y represents (CH)group or 0 atom or S atom, and where n=0-3.


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