The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 19, 2016

Filed:

Nov. 20, 2014
Applicant:

Advanced Liquid Logic, Inc., San Diego, CA (US);

Inventors:

Cyril Delattre, Izeaux, FR;

Arnaud Rival, St Martin d'Hères, FR;

Vijay Srinivasan, Cary, NC (US);

Assignees:

Advanced Liquid Logic, Inc., San Diego, CA (US);

Illumina France SARL, Paris, FR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/02 (2006.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/0268 (2013.01); B01L 3/50273 (2013.01); B01L 3/502723 (2013.01); B01L 3/502784 (2013.01); B01L 2200/06 (2013.01); B01L 2200/0605 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/088 (2013.01); B01L 2300/089 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/1827 (2013.01); B01L 2400/043 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0409 (2013.01); B01L 2400/0415 (2013.01); B01L 2400/0427 (2013.01); B01L 2400/0442 (2013.01); B01L 2400/0448 (2013.01);
Abstract

During droplet operations in a droplet actuator, bubbles often form in the filler fluid in the droplet operations gap and interrupt droplet operations. The present invention provides methods and systems for performing droplet operations on a droplet in a droplet actuator comprising maintaining substantially consistent contact between the droplet and an electrical ground while conducting multiple droplet operations on the droplet in the droplet operations gap and/or reducing the accumulation of electrical charges in the droplet operations gap during multiple droplet operations. The methods and systems reduce or eliminate bubble formation in the filler fluid of the droplet operations gap, thereby permitting completion of multiple droplet operations without interruption by bubble formation in the filler fluid in the droplet operations gap.


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