The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 19, 2016
Filed:
Jul. 29, 2015
Applicant:
Acell, Inc., Columbia, MD (US);
Inventors:
Kimberly A. Kentner, Columbia, MD (US);
Katherine A. Stuart, Columbia, MD (US);
Abram D. Janis, Columbia, MD (US);
Assignee:
ACell, Inc., Columbia, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/02 (2006.01); A61K 35/37 (2015.01); A61K 35/38 (2015.01); A61K 35/407 (2015.01); A61L 27/36 (2006.01); A61L 27/50 (2006.01); A61L 27/54 (2006.01); A61L 27/52 (2006.01);
U.S. Cl.
CPC ...
A61L 27/3633 (2013.01); A61L 27/50 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61L 2300/412 (2013.01); A61L 2300/414 (2013.01);
Abstract
The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ECM material can be created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels.