The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 19, 2016
Filed:
Feb. 15, 2011
Applicants:
Dolores Schendel, Munich, DE;
Rudolf Wank, Munich, DE;
Inventors:
Dolores Schendel, Munich, DE;
Rudolf Wank, Munich, DE;
Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/15 (2015.01); A61K 35/28 (2015.01); A61K 48/00 (2006.01); A61K 39/00 (2006.01); C12N 5/10 (2006.01); C12N 5/078 (2010.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); A61K 48/00 (2013.01); A61K 2039/5154 (2013.01); A61K 2039/5156 (2013.01);
Abstract
The present invention relates to semi-allogeneic antigen-presenting cells into which proteins and/or peptides or RNA or DNA or cDNA, respectively, encoding said proteins and/or peptides which are overexpressed in tumor cells or which are derived from autologous tumor cells or different tumor cells or different tumor cell lines have been introduced. Furthermore the invention relates to methods for the generation of these semi-allogeneic antigen-presenting cells as well as to the use thereof in the treatment of tumor diseases.