The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 19, 2016

Filed:

Mar. 07, 2012
Applicants:

Michael A. Teitell, Tarzana, CA (US);

Carla M. Koehler, Los Angeles, CA (US);

Geng Wang, Los Angeles, CA (US);

Inventors:

Michael A. Teitell, Tarzana, CA (US);

Carla M. Koehler, Los Angeles, CA (US);

Geng Wang, Los Angeles, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 31/7088 (2006.01); C12N 15/87 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7088 (2013.01); C12N 15/11 (2013.01); C12N 15/1137 (2013.01); C12N 15/87 (2013.01); C12Y 207/07008 (2013.01); C12N 2310/14 (2013.01);
Abstract

Disclosed herein are methods of manipulating the processing, targeting, and/or internalization of a nucleic acid molecule. Also disclosed are recombinant and/or isolated nucleic acid molecules having a first nucleic acid sequence, which is a wild-type sequence or an altered sequence, directly or indirectly linked to a second nucleic acid sequence which is a mitochondria localization sequence, an RNA import sequence, or a combination thereof, and methods of using thereof.


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