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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9238033 B1

PDFFull Text
Date of Patent:
Jan. 19, 2016

Filed:

Apr. 24, 2013

Pharmaceutical composition containing kw-6002 and fluoxetine or paroxentine

Applicant:

Kyowa Hakko Kirin Co., Ltd., Chiyoda-ku, Tokyo, JP;

Inventors:

Hiroshi Kase, Koganei, JP;

Minoru Kobayashi, Shizuoka, JP;

Shizuo Shiozaki, Shizuoka, JP;

Akihisa Mori, Chiyoda-ku, JP;

Naoki Seno, Shizuoka, JP;

Assignee:

KYOWA HAKKO KIRIN CO., LTD., Tokyo, JP;

Attorney:

Fitzpatrick, Cella, Harper & Scinto

Primary Examiner:

Sarah Pihonak

Int. Cl.
CPC ...
A61K 31/522 (2006.01); A61K 31/138 (2006.01); A61K 31/137 (2006.01); A61K 31/335 (2006.01); A61K 31/343 (2006.01); A61K 31/36 (2006.01); A61K 31/38 (2006.01); A61K 31/381 (2006.01); A61K 31/435 (2006.01); A61K 31/496 (2006.01); A61K 31/52 (2006.01); A61K 31/5375 (2006.01); A61K 31/55 (2006.01); A61K 31/553 (2006.01); A61K 31/16 (2006.01); A61K 31/4525 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/522 (2013.01); A61K 31/137 (2013.01); A61K 31/16 (2013.01); A61K 31/335 (2013.01); A61K 31/343 (2013.01); A61K 31/36 (2013.01); A61K 31/38 (2013.01); A61K 31/381 (2013.01); A61K 31/435 (2013.01); A61K 31/4525 (2013.01); A61K 31/496 (2013.01); A61K 31/52 (2013.01); A61K 31/5375 (2013.01); A61K 31/55 (2013.01); A61K 31/553 (2013.01); A61K 45/06 (2013.01); A61K 31/138 (2013.01);
Abstract

The present invention provides pharmaceutical compositions, which are useful for treatment of depression and the like, and which comprises a compound having an adenosine Areceptor antagonistic activity such as (E)-8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione or a pharmaceutically acceptable salt thereof and an antidepressant drug (for example, a tricyclic antidepressant, a tetracyclic antidepressant, a selective serotonin reuptake inhibitor, a selective noradrenalin reuptake inhibitor, a dopamine reuptake inhibitor, a serotonin-noradrenalin reuptake inhibitor, monoamine oxidase inhibitor, a 5-HTantagonist or the like), and the like.

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