The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2016
Filed:
Apr. 13, 2012
David Jackson, Heidelberg, DE;
Theodoros Soldatos, Heidelberg, DE;
Guillaume Taglang, Heidelberg, DE;
Alexander Zien, Heidelberg, DE;
Stephan Brock, Heidelberg, DE;
David Jackson, Heidelberg, DE;
Theodoros Soldatos, Heidelberg, DE;
Guillaume Taglang, Heidelberg, DE;
Alexander Zien, Heidelberg, DE;
Stephan Brock, Heidelberg, DE;
MOLECULAR HEALTH GMBH, Heidelberg, DE;
Abstract
The present disclosure describes systems and methods for predicting a likely side effect profile for even new, untested medications. A predicted side effect profile may be generated based on intersections of side effect profiles of other medications that affect the same or related molecular entities, such as the nearby target proteins, involve the same pathways, or are otherwise similarly related. To generate a predicted side effect profile for a new drug targeting a novel or previously un-targeted protein target, an analyzer may query an adverse event database for records pertaining to patients who have taken drugs or combinations of drugs that target or affect molecular entities in the vicinity of the novel target within a global molecular entity graph, and, in some embodiments, may retrieve a plurality of adverse event records and generate an intersection of side effects associated with related targets to predict likely side effects for the novel target.