The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2016
Filed:
Feb. 20, 2012
Eun Wie Cho, Daejeon, KR;
Chang Gyu Heo, Daejeon, KR;
Jeong Heon Ko, Daejeon, KR;
MI Kyung Woo, Daejeon, KR;
Hyang Sook Yoo, Daejeon, KR;
Hai Min Hwang, Daejeon, KR;
Eun Wie Cho, Daejeon, KR;
Chang Gyu Heo, Daejeon, KR;
Jeong Heon Ko, Daejeon, KR;
Mi Kyung Woo, Daejeon, KR;
Hyang Sook Yoo, Daejeon, KR;
Hai Min Hwang, Daejeon, KR;
Abstract
The present invention relates to a cytokeratin 8/18 complex-specific autoantibody or a fragment comprising an antigen-binding site (paratope) thereof, the use thereof in the diagnosis of breast cancer, a polypeptide having an amino acid sequence of an epitope specifically binding to the autoantibody, a composition for diagnosing breast cancer comprising an agent capable of measuring an expression level of the autoantibody or the fragment comprising an antigen-binding site thereof, a hybridoma cell line producing the autoantibody, and a kit for diagnosing breast cancer comprising the composition of the present invention. Further, the present invention relates to a method for diagnosing breast cancer, comprising the step of detecting the cytokeratin 8/18 complex-specific autoantibody or the fragment comprising the antigen-binding site thereof using the composition of the present invention, and a method for screening a therapeutic agent for breast cancer using the autoantibody.