The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 2016

Filed:

Oct. 07, 2014
Applicant:

Canon U.s. Life Sciences, Inc., Rockville, MD (US);

Inventors:

Bradley S. Thomas, Timonium, MD (US);

Johnathan S. Coursey, Rockville, MD (US);

Kenton C. Hasson, Germantown, MD (US);

Hongye Liang, Clarksville, MD (US);

Assignee:

Canon U.S. Life Sciences, Inc., Rockville, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 15/06 (2006.01); G01N 33/00 (2006.01); C12Q 1/68 (2006.01); B01L 3/00 (2006.01); B01L 7/00 (2006.01); G01N 21/03 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/686 (2013.01); B01L 3/5027 (2013.01); B01L 7/52 (2013.01); B01L 2300/0858 (2013.01); B01L 2300/18 (2013.01); G01N 21/0303 (2013.01); Y10T 436/11 (2015.01);
Abstract

A microfluidic chip includes microfluidic channels, elements for thermally and optically isolating the microfluidic channels, and elements for enhancing the detection of optical signal emitted from the microfluidic channels. The thermal and optical isolation elements may comprise barrier channels interposed between adjacently-arranged pairs of microfluidic channels for preventing thermal and optical cross-talk between the adjacent microfluidic channels. The isolation element may alternatively comprise reflective film embedded in the microfluidic chip between the adjacent microfluidic channels. The signal enhancement elements comprise structures disposed adjacent to the microfluidic channels that reflect light passing through or emitted from the microfluidic channel in a direction toward a detector. The structures may comprise channels or a faceted surface that redirects the light by total internal reflection or reflective film material embedded in the microfluidic chip.


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