The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 2016

Filed:

Sep. 26, 2012
Applicant:

Sample6 Technologies, Inc., Boston, MA (US);

Inventors:

Timothy Kuan Ta Lu, Charlestown, MA (US);

Michael Sandor Koeris, Natick, MA (US);

Brett Smith Chevalier, Malden, MA (US);

Jason Wyatt Holder, Somerville, MA (US);

Gregory John McKenzie, Arlington, MA (US);

Daniel Robert Brownell, Arlington, MA (US);

Assignee:

Sample6 Technologies, Inc., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); C12P 19/34 (2006.01); C12N 15/10 (2006.01); C12N 15/81 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12P 19/34 (2013.01); C12N 15/10 (2013.01); C12N 15/81 (2013.01); C12N 15/86 (2013.01); C12N 2795/10143 (2013.01); C12N 2795/10243 (2013.01); C12N 2800/206 (2013.01);
Abstract

This disclosure provided methods of cloning a phage genome. Also provided are methods of making a recombinant phage genome. In some embodiments the phage genome is engineered to comprise a heterologous nucleic acid sequence, for example a sequence comprising an open reading frame. In some embodiments the phage genome is cloned in a yeast artificial chromosome. Recombinant phage genomes and recombinant phage are also provided. In some embodiments the methods are high throughput methods such as methods of making a plurality of recombinant phage genomes or recombinant phage. Collections of recombinant phage genomes and recombinant phage are also provided.


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