The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 2016

Filed:

Oct. 14, 2010
Applicants:

Jan Van Breugel, Woudrichem, NL;

Willem Jacob Groot, Dordecht, NL;

Peter Paul Jansen, Oss, NL;

Inventors:

Jan Van Breugel, Woudrichem, NL;

Willem Jacob Groot, Dordecht, NL;

Peter Paul Jansen, Oss, NL;

Assignee:

Purac Biochem BV, Gorinchem, NL;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 7/42 (2006.01); C12P 7/56 (2006.01); C12P 1/00 (2006.01); C12P 7/46 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12P 1/00 (2013.01); C12P 7/46 (2013.01); C12P 7/56 (2013.01);
Abstract

A fermentation process includes contacting a carbohydrate source with a microorganism in an aqueous fermentation broth to form a fermentation product which is a salt or a product with a boiling point above the boiling point of water. The fermentation process is carried out at a pressure which is below atmospheric pressure and at least at the value where the reaction medium is at its boiling point at the fermentation temperature. Water is evaporated and removed from the reactor during the fermentation in an amount which is at least 20% of the volume of liquid present in the reactor at the start of the fermentation. A fermentation process at reduced pressure while removing a substantial amount of water removes a surplus of water in the system, ensures removal of reaction heat, and may lead to improved fermentation quality.


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