The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2016
Filed:
Aug. 20, 2014
Applicant:
Psioxus Therapeutics Limited, London, GB;
Inventors:
Paul Harden, Brentwood, CA (US);
Terry Hermiston, Corte Madera, CA (US);
Irene Kuhn, Richmond, CA (US);
Assignee:
PSIOXUS THERAPEUTICS LIMITED, London, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/63 (2006.01); C12N 7/00 (2006.01); C12N 15/86 (2006.01); A61K 38/45 (2006.01); A61K 35/761 (2015.01); A61K 35/00 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); A61K 35/761 (2013.01); A61K 38/45 (2013.01); C12N 15/86 (2013.01); C12N 2710/10021 (2013.01); C12N 2710/10032 (2013.01); C12N 2710/10051 (2013.01); C12N 2710/10321 (2013.01); C12N 2710/10332 (2013.01); C12N 2710/10343 (2013.01); C12N 2710/10344 (2013.01);
Abstract
The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.