The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2016
Filed:
Apr. 25, 2014
Applicant:
H. Lundbeck A/s, Valby-Copenhagen, DK;
Inventors:
Olav Michael Anderson, Skamby, DK;
Anders Nykjaer, Risskov, DK;
Assignee:
H. Lundbeck A/S, Valby, DK;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/40 (2006.01); A61K 39/42 (2006.01); C07K 16/26 (2006.01); C07K 14/47 (2006.01); C07K 14/705 (2006.01); G01N 33/68 (2006.01); A61K 38/07 (2006.01); A61K 38/08 (2006.01); A61K 38/10 (2006.01); A61K 38/17 (2006.01); A61K 39/395 (2006.01); C07K 5/11 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); G01N 33/566 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/26 (2013.01); A61K 38/07 (2013.01); A61K 38/08 (2013.01); A61K 38/10 (2013.01); A61K 38/1709 (2013.01); A61K 39/3955 (2013.01); C07K 5/1019 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C07K 14/4703 (2013.01); C07K 14/4711 (2013.01); C07K 14/70571 (2013.01); G01N 33/566 (2013.01); G01N 33/6896 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); C07K 2317/76 (2013.01); G01N 2500/02 (2013.01);
Abstract
The present invention provides agents for inhibiting binding of a pro-neurotrophin to a Vps1 Op-domain receptor, in particular the binding of a pro-NGF or a pro-BDNF to a Sortilin receptor. The invention thus provides agents for the manufacture of a medicament, for treating and/or preventing disease or disorders such as but not limited to neurological, neuropsychiatric and ocular diseases, disorders, and degeneration as well as obesity, diabetes, pain and/or nociception in an individual.