The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2016
Filed:
Feb. 05, 2014
Applicant:
City of Hope, Duarte, CA (US);
Inventors:
David Horne, Altadena, CA (US);
Jun Xie, Monrovia, CA (US);
Angela L. Perkins Harki, Minneapolis, MN (US);
Richard Jove, Glendora, CA (US);
Sangkil Nam, South Pasadena, CA (US);
Wendong Huang, Glendora, CA (US);
Rongzhen Xu, Hangzhou, CN;
Assignee:
CITY OF HOPE, Duarte, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/147 (2006.01); A61K 31/4745 (2006.01);
U.S. Cl.
CPC ...
C07D 491/147 (2013.01); A61K 31/4745 (2013.01);
Abstract
The invention provides novel berbamine derivatives, and compositions or pharmaceutical compositions thereof. These berbamine derivatives have shown higher potency in killing cancer/tumor cells comparing to berbamine, and can be used in cancer/tumor treatments.