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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9233957 B1

PDFFull Text
Date of Patent:
Jan. 12, 2016

Filed:

Jun. 11, 2012

5-carbamoyl-adamantan-2-yl amide derivatives, pharmaceutically acceptable salts thereof and preparation process thereof

Applicants:

Coo-min Chung, Daejeon, KR;

Choon-ho Ryu, Daejeon, KR;

Yoon-kyeong Lee, Seoul, KR;

Jin-sook Moon, Gyeongsangnam-do, KR;

Hye-sung Lee, Daejeon, KR;

Seon-jeong Lee, Daejeon, KR;

Kyung-seok OH, Daejeon, KR;

Inventors:

Coo-Min Chung, Daejeon, KR;

Choon-Ho Ryu, Daejeon, KR;

Yoon-Kyeong Lee, Seoul, KR;

Jin-Sook Moon, Gyeongsangnam-do, KR;

Hye-Sung Lee, Daejeon, KR;

Seon-Jeong Lee, Daejeon, KR;

Kyung-Seok Oh, Daejeon, KR;

Assignee:

SK BIOPHARMACEUTICALS CO., LTD., Seoul, KR;

Attorney:

Harness, Dickey & Pierce, P.L.C.

Primary Examiner:

Valerie Rodriguez-Garcia

Int. Cl.
CPC ...
C07D 207/34 (2006.01); C07D 213/81 (2006.01); C07D 213/89 (2006.01); C07D 215/48 (2006.01); C07D 215/60 (2006.01); C07D 417/04 (2006.01); C07D 333/38 (2006.01); C07D 261/10 (2006.01); C07D 307/56 (2006.01); C07D 261/18 (2006.01); C07D 307/68 (2006.01); C07D 401/04 (2006.01); C07D 413/04 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
C07D 417/04 (2013.01); C07D 207/34 (2013.01); C07D 213/81 (2013.01); C07D 213/89 (2013.01); C07D 215/48 (2013.01); C07D 215/60 (2013.01); C07D 261/10 (2013.01); C07D 261/18 (2013.01); C07D 307/56 (2013.01); C07D 307/68 (2013.01); C07D 333/38 (2013.01); C07D 401/04 (2013.01); C07D 413/04 (2013.01); C07D 413/12 (2013.01);
Abstract

Provided are a novel derivative of 5-carbamoyl adamantan-2-yl amide of Formula (I), or a pharmaceutically acceptable salt thereof, and a pharmaceutical use thereof for inhibiting the activity of 11β-hydroxystreroid dehydrogenase type 1 (11b-HSD1) or for preventing and/or treating various diseases mediated by 11β-hydroxystreroid dehydrogenase type 1.

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