The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2016
Filed:
Jan. 24, 2012
Deepak Bansal, Uttar Pradesh, IN;
Himanchal Mishra, Uttar Pradesh, IN;
Shailendr Kumar Dubey, Uttar Pradesh, IN;
Alka Srivastava Choudhary, Uttar Pradesh, IN;
Dharam Vir, Uttar Pradesh, IN;
Ashutosh Agarwal, Uttar Pradesh, IN;
Deepak Bansal, Uttar Pradesh, IN;
Himanchal Mishra, Uttar Pradesh, IN;
Shailendr Kumar Dubey, Uttar Pradesh, IN;
Alka Srivastava Choudhary, Uttar Pradesh, IN;
Dharam Vir, Uttar Pradesh, IN;
Ashutosh Agarwal, Uttar Pradesh, IN;
Jubilant Life Sciences, Ltd., Uttar Pradesh, IN;
Abstract
The present invention relates to an improved process for the preparation of azilsartan or its esters or salts thereof. Specifically, the invention provides a method for the preparation of highly pure methyl 1-[[2'-(4,5-dihydro-5-oxo-4H-1,2,4-oxa-diazol-3-yl)biphenyl-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate an intermediate compound of formula (4) for azilsartan medoxomil with reduced content of desethyl impurity. The invention also involves the use of highly pure methyl 1-[[2′-(4,5-dihydro-5-oxo-4H-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate in the preparation of azilsartan or its esters or salts thereof, preferably medoxomil with reduced content of desethyl impurity.