The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 2016

Filed:

Sep. 17, 2010
Applicants:

Milton L. Brown, Brookeville, MD (US);

Yali Kong, Centreville, VA (US);

Christopher Stuart Wilcox, Washington, DC (US);

Inventors:

Milton L. Brown, Brookeville, MD (US);

Yali Kong, Centreville, VA (US);

Christopher Stuart Wilcox, Washington, DC (US);

Assignee:

Georgetown University, Washington, DC (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/4184 (2006.01); A61K 31/45 (2006.01); A61K 31/416 (2006.01); A61K 31/454 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 31/416 (2013.01); A61K 31/4184 (2013.01); A61K 31/45 (2013.01); A61K 31/454 (2013.01); A61K 45/06 (2013.01);
Abstract

One aspect of the invention relates to compounds, compositions and methods for treating oxidative stress and/or hypertension. In certain embodiments, the invention relates to a mixture of tempol and an angiotensin receptor blocker (ARB) and the use of said mixture to treat oxidative stress and/or hypertension. In certain embodiments, the invention relates to a tempol/ARB adduct and the use of said adduct to treat oxidative stress and/or hypertension.


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