The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2016
Filed:
Jan. 04, 2013
Applicant:
Janssen R&d Ireland, Co. Cork, IE;
Inventors:
Koen Vandyck, Paal-Beringen, BE;
Geerwin Yvonne Paul Haché, Kapellen, BE;
Geert Rombouts, Borsbeek, BE;
Wim Gaston Verschueren, Berchem, BE;
Pierre Jean-Marie Raboisson, Rosieres, BE;
Assignee:
Janssen Sciences Ireland UC, Little Island, Co. Cork, IE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/541 (2006.01); C07D 239/22 (2006.01); C07D 401/04 (2006.01); C07D 403/04 (2006.01); C07D 417/04 (2006.01); C07D 471/10 (2006.01); C07D 491/107 (2006.01); A61K 31/505 (2006.01); A61K 31/506 (2006.01); A61K 31/513 (2006.01); A61K 31/527 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); C07D 487/10 (2006.01);
U.S. Cl.
CPC ...
C07D 239/22 (2013.01); A61K 31/505 (2013.01); A61K 31/506 (2013.01); A61K 31/513 (2013.01); A61K 31/527 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); A61K 45/06 (2013.01); C07D 401/04 (2013.01); C07D 403/04 (2013.01); C07D 417/04 (2013.01); C07D 471/10 (2013.01); C07D 487/10 (2013.01); C07D 491/107 (2013.01);
Abstract
Inhibitors of HBV replication of formula (I) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein R-R, B and Z have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.