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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9233933 B1

PDFFull Text
Expired
Date of Patent:
Jan. 12, 2016

Filed:

Jan. 04, 2013

4,4-disubstituted-1,4-dihydropyrimidines and the use thereof as medicaments for the treatment of hepatitis b

Applicant:

Janssen R&d Ireland, Co. Cork, IE;

Inventors:

Koen Vandyck, Paal-Beringen, BE;

Geerwin Yvonne Paul Haché, Kapellen, BE;

Geert Rombouts, Borsbeek, BE;

Wim Gaston Verschueren, Berchem, BE;

Pierre Jean-Marie Raboisson, Rosieres, BE;

Assignee:

Janssen Sciences Ireland UC, Little Island, Co. Cork, IE;

Attorney:

Andrea Jo Kamage

Primary Examiner:

Alexander R Pagano

Int. Cl.
CPC ...
A61K 31/541 (2006.01); C07D 239/22 (2006.01); C07D 401/04 (2006.01); C07D 403/04 (2006.01); C07D 417/04 (2006.01); C07D 471/10 (2006.01); C07D 491/107 (2006.01); A61K 31/505 (2006.01); A61K 31/506 (2006.01); A61K 31/513 (2006.01); A61K 31/527 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); C07D 487/10 (2006.01);
U.S. Cl.
CPC ...
C07D 239/22 (2013.01); A61K 31/505 (2013.01); A61K 31/506 (2013.01); A61K 31/513 (2013.01); A61K 31/527 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); A61K 45/06 (2013.01); C07D 401/04 (2013.01); C07D 403/04 (2013.01); C07D 417/04 (2013.01); C07D 471/10 (2013.01); C07D 487/10 (2013.01); C07D 491/107 (2013.01);
Abstract

Inhibitors of HBV replication of formula (I) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein R-R, B and Z have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.

Find Patent Forward Citations

Vandyck, Koen. (2016). 4,4-disubstituted-1,4-dihydropyrimidines and the use thereof as medicaments for the treatment of hepatitis b (U.S. Patent No. 9233933). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9233933

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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